Florence Day Trip from Rome. Visit Florence on day trip from Rome and see its top attractions with an expert guide at your side! Start with a guided tour of the incredible Accademia Gallery, seeing Michelangelo’s ‘David’ and Botticelli’s ‘Madonna and Child,’ and then explore the city on a comprehensive walking tour. Gaze in awe at Brunelleschi’s Dome at Florence Duomo and then finish your time in Florence with a visit to one of its legendary leather-making schools to see a time-honored craft in action. Book and Save 10% Off Florence Day Trip from Rome.