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5-Day Best of Italy Trip. Visit Italyâ€™s top destinations â€” Florence, Siena, Assisi, Venice and more â€” on this 5-day tour from Rome. With a mix of free time and guided portions, this is an ideal introduction to the regions of Umbria and Tuscany. Check out the historical cities of Assisi, Siena and Montepulciano; soak up Florenceâ€™s wealth of art and architecture; and then continue to Padua and Bologna before arriving in Venice, home to sights like St Mark's Basilica. Four nights of accommodation in Florence and Venice and round-trip transport by coach are included. Book this Tour and Save 10%! 5-Day Best of Italy Trip.