5-Day Best of Italy Trip. Visit Italy’s top destinations — Florence, Siena, Assisi, Venice and more — on this 5-day tour from Rome. With a mix of free time and guided portions, this is an ideal introduction to the regions of Umbria and Tuscany. Check out the historical cities of Assisi, Siena and Montepulciano; soak up Florence’s wealth of art and architecture; and then continue to Padua and Bologna before arriving in Venice, home to sights like St Mark's Basilica. Four nights of accommodation in Florence and Venice and round-trip transport by coach are included. Book this Tour and Save 10%! 5-Day Best of Italy Trip.