Book American Airlines Flights with $30 Off!! American Airlines is a major American air carrier that was founded in 1926. Headquartered in Fort Worth, Texas, American Airlines is the largest airline in the world by the total number of destinations served, revenue, fleet size and scheduled passenger-kilometers flown. American Airlines is one of the founding members of the third largest airline alliance in the world Oneworld Alliance. It has a total of 10 hubs - Charlotte Douglas International Airport, Los Angeles International Airport, Dallas/Fort Worth International Airport, O'Hare International Airport, Miami International Airport, Philadelphia International Airport, Ronald Reagan Washington National Airport, LaGuardia Airport, Phoenix Sky Harbor International Airport and John F. Kennedy International Airport. Its frequent flyer program is called Advantage.